Clobazam (Onfi) visual mnemonics
Excerpt from Cafer's Mood Stabilizers and Antiepileptics Clobazam (Onfi) “Clob ber On wi- fi ” Pronunciation: KLOE ba zam / ON fee ❖ 1,5 benzodiazepine ❖ Rapid onset ❖ Long duration ❖ DEA Schedule IV FDA approved for: ❖ Seizures of Lennox-Gastaut syndrome (LGS) Clobazam, long available in other countries, was finally FDA approved in the US in 2011 for adjunctive treatment of seizures associated with Lennox-Gastaut Syndrome (ages 2 years or older). Outside of the US it was marketed as an anxiolytic since 1975 and an anticonvulsant since 1984. Lennox-Gastaut syndrome (LGS), pronounced gas-TOE , is a type of childhood-onset epilepsy characterized by a triad of symptoms including multiple seizure types, intellectual impairment, and characteristic EEG findings. Clobazam is a Schedule IV controlled substance like all of the other benzos. Alcohol ingestion increases the blood concentration of clobazam by about 50%. So, what is so special about c...